Silhouettes (Public Domain) in front of blood cells (Public Domain) and a gene.

Rh-Negative Blood: An Exotic Bloodline or Random Mutation?


Most people who have the Rh blood type are Rh-positive. There are also instances, however, where people are Rh-Negative. Health problems may occur for the unborn child of a mother with Rh-Negative blood when the baby is Rh-Positive. This has led some to suggest that Rh-Negative blood must be of a non-human origin. Theories range from supernatural ones such as being of divine descent or membership in a divinely chosen people-group, to more scientific or pseudoscientific explanations such as interbreeding with extraterrestrials. The majority of scientists who have studied the blood type have concluded that it is most likely just a random mutation. This explanation seems to be the one most consistent with available evidence and the one that is most able to withstand Occam’s Razor.

What is unusual about Rh-Negative blood is that the gene for it is surprisingly common despite being potentially harmful. When a woman who is Rh-Negative is pregnant with a child that is Rh-Positive, the mother’s immune system creates protective anti-bodies to the Rh-Positive blood, and her blood essentially becomes toxic to the child. To some people, this looks like the mother’s body is rejecting the baby - which has led them to suggest that perhaps the reason for the rejection is incompatibility based on the mother and child being of different species. Others suggest that lineages with the gene for Rh-Negative blood are merely special in some way and were not meant to be mixed with lineages which are predominantly Rh-Positive.

Blood type testing.

Blood type testing. (ec-jpr/ CC BY NC ND 2.0 )

Rh-Negative Blood Lineages

One population which contains an unusually high frequency of the gene for the Rh-Negative blood type are the Basques from northeastern Spain. The Basques have the highest incidence of the gene out of any population in the world. The Basques also speak a non-Indo-European language and have genetic markers that pre-date the rise of agriculture. This has led to speculation that Rh-Negative blood is related to Cro-Magnon ancestry going back to the upper Paleolithic period in Europe.

Among the more exotic theories is the idea that the Rh-Negative gene represents a separate branch of humanity that intermarried with the branch that came out of Africa. One blogger has gone as far as to say that those with Rh-Negative blood are descendants of the Hyperborean race, which they believe to be the original human race. Followers of this idea believe that this race was blonde-haired and blue-eyed and included most major spiritual teachers in history, including Jesus.

An artistic representation of Hyperborean women.

An artistic representation of Hyperborean women. ( Youtube Screenshot )

Some people who are not satisfied with the idea that those with RH- blood are another form of humanity have suggested that the trait originates from extraterrestrials either interbreeding with humans or creating humans through genetic engineering.

The Role of Genetics in Rh-Negative Blood

This unusual trait can, however, also be explained in terms of relatively mundane human genetics and natural selection. One possibility is that the gene for Rh-Negative blood has some sort of selective advantage that outweighed the negative consequences of having Rh-Negative blood.

A well-known example of this phenomenon would be the case of sickle cell anemia and malaria. A large percentage of the population in west Africa where malaria is common consists of carriers of the gene for sickle-cell anemia, although they don’t have the disease themselves. The reason is that just carrying the gene for sickle cell anemia gives the person carrying it immunity to Malaria. Although sickle-cell anemia is harmful, even deadly, carrying the gene gives a selective advantage and therefore it is much more common than would be expected.

Sickle-cell disease is inherited in the autosomal recessive pattern.

Sickle-cell disease is inherited in the autosomal recessive pattern. ( CC BY SA 3.0 )

Scientists studying the effects of Rh-Negative blood have found that individuals carrying the gene for Rh-Negative blood are more resistant to certain parasites such as toxoplasma, which can threaten unborn children. It has also been found that there are more carriers of the gene in areas where toxoplasma is more common. This suggests that carriers of the gene for Rh-Negative blood might be more common than expected because there is a positive selective advantage, greater resistance to parasites, that outweighs the negative, possibly having a pregnancy where the mother’s blood endangers the unborn child.

Dividing Toxoplasma gondii, an obligate intracellular human parasite. (Ke Hu and John M. Murray/ CC BY 4.0 )

As a result, it could be that some populations contain a higher occurrence rate of the gene not because of a unique lineage but because they are adapted to a region with a high prevalence of certain parasites such as toxoplasma. This would explain why the gene occurs in high frequency in populations that are not really connected other than the fact that they are  Homo Sapiens,  such as Basques and certain Jewish populations.

The Basques have an ancestry that, with other European groups, goes back to the European Upper Paleolithic. Yet the Jews ultimately descend from relatively recent Middle Eastern populations. This would make sense if the reason for the prevalence of the gene was because both the ancestral Basque and Jewish populations originated in an environment with similar selective factors rather than being of a common lineage.

Basque women in Bayonne (1852).

Basque women in Bayonne (1852). ( Public Domain )

Although it could still be that there is a common, unique ancestral lineage connecting populations with high prevalence of Rh-Negative blood, the fact that the populations where the gene occurs in high prevalence appear otherwise unrelated to each other makes it less likely and in need of more evidence.

Could Rh-Negative Blood Come from Extraterrestrials?

The extraterrestrial explanation is even more problematic because the Rh-Negative gene is clearly a variation of an otherwise completely human gene. Unless it was specifically engineered by extraterrestrials from a pre-existing human gene, it is unlikely that it comes from anything other than  Homo Sapiens .

The other problem with the Rh-Negative blood type being the result of hybridization with extraterrestrials is that extraterrestrials are likely to have a completely different biology and genome than human beings. Their genome might not even be based on DNA - but something else such as RNA, or some exotic form of genetic storage that never evolved on Earth. This would make any viable hybrids very improbable if not impossible. As the astronomer Carl Sagan would have put it, it would be easier to make a human-tulip hybrid, than a human-extraterrestrial hybrid.

An artist’s representation of an extraterrestrial.

An artist’s representation of an extraterrestrial. ( Public Domain )

The unlikelihood and uncertainty of the other options make the explanation that the Rh-Negative blood type is just a mutation that became common in some populations due to a selective advantage the most likely option. It is also the one that most easily survives the application of Occam’s Razor. If this blood type was because of another human species, let alone extraterrestrials, many more unnecessary assumptions that are difficult to verify have to be made. As a result, the evidence currently points toward little more than an ordinary mutation as the cause of the Rh-Negative blood phenotype.

Top Image: Silhouettes ( Public Domain ) in front of blood cells ( Public Domain ) and a gene. ( Public Domain )

By Caleb Strom


“Blood Types” by Khameeka Kitt (2010). The Tech Museum of Innovation  Ask a Geneticist . Available at:

“Origin Theories of the Rh-Negative Blood Factor.” Rh-Negative Registry. Available at:

“Theory: Jesus "Yashua's" Nazarene” by “Neil” (N.D.). Rh-Negative Registry. Available at:

Gurevitch, J., D. Hermoni, and Z. Polishuk. "Rh blood types in Jerusalem Jews."  Annals of Human

Genetics 16.1 (1951): 129-130.

Chalmers, J. N., Elizabeth W. Ikin, and A. E. Mourant. "The ABO, MN and Rh blood groups of the Basque

people." American Journal of Physical Anthropology  7.4 (1949): 529-544.


To be fair, much of the research on human blood type is lacking, especially Rh negatives & its peculiarity. I have heard some of it is suppresed (but that’s unconfirmed). To be honest, the whole thing sounds like “cancer research”.

I agree that the author of this is biased and ignorant to say the least. My mother Onegative and Father A negative. There is a coverup going on about this. Egyptian Pharoahs had Negative blood as well as the Royal bloodlines. The way he casually brushes aside items is sickening. That is how this world is . Important people are disregarded and the ignorant held up. It is a rare blood type. Africans do not have it. It is high in the True Israelite bloodlines. Who by the way are the ancestors of the true Kings and Queens of Europe and The Scandanavians and UK.

Sir Clerke

This article is purely speculative. It is bias, and claims that RH negative is a MALFORMATION of genetics resulting in a mutation with no sound scientific evidence. I am O-. Myou O- is an Italian trait where most of my "MUTATED" family lives to be over 100 years old, as my O- "MUTATED" great grandmother lived to be 103 years old. This article is repulsive and possibly based in a Darwin socialist theory.

Things like this shouldn't be on the Internet. It's trash.

Absolutely correct. Darwins theory is easily disproved. He knew it himself. There is no better book written that is one hundred percent fact and can be proven divine than the King James 1611. RH negative is a thing that has become of interest lately.

Sir Clerke

This writer needs to read as most do who and how both Blood Types and Blood Factors came about. First off.... Dr Wiener did not invent either of them. What he did was take his own personal bias and ideas about humans being related to monkeys from Darwin's 'Theory of Evolution'. Which he got from his Grandfather and added his own Theory of 'Natural Selection' and even he failed to prove it is how 'Eyeballs' came about from 'Natural Selection' (read up on that whole debacle where he was unable to show how Eyeballs could ever come from his 'Natural Selection').

Now think about it; if man evolved from monkeys, and in fact, every animate object on earth from smallest amoeba in a never-ending chain of non-intelligent natural selection.... why hasn't mankind jumped to the next level in that chain? Why haven't monkeys become humans... since they've been around so long? Why haven't we as so more evolved, figured out how to move stones in building like the ancients did weighing 1000 Tons and stack them on top of one another at that? Forget the Greeks or Romans..... they weren't quite as Evolved as the Ancients.... I guess! ;-P

And Caleb... if 'Natural Selection vs Intelligent Design' is so irrefutable.... why hasn't Darwin's Theories been made into scientific fact... yet? But hey... let's forget that debate for a second and tell me how us Rh-D Negatives as the Recessive Genetic Traits go, are still around? When according to Darwin's own Theories the Dominant Rh-D Positives should have already made all of us Rh-Negatives extinct through 'Natural Selection' by now?

Instead, we are still somehow finding other Rh-Negatives to have babies with. Who in turn meet other Rh-Negatives and they have maintained about the same percentages for 1000's of years. Tell us how that's possible if there is no intelligent design in the process.... or in that dirty word... CREATION with a Purpose coded into Mankind's very existence?

My entire family is Rh-D Negative. As such, being of two distinctly separate branches of the R1b Haplogroup as one Celtic and Celtiberian coupled with Basque are running near 100% Rh-D Negative Bloodlines as a Recessive Genome carrying family. Better yet with so many A-Negatives just so happening to meet up B-Negatives (if Natural Selection is true?) to in turn have kids that turn out as AB-Negatives? Which make up only 0.5% of the World's Population as for the rarest Blood Factor Group on the Planet still today!

Now let's get back to real SCIENCE and how Blood Types and Factors came about in the first place and I just want to read the true story of how Dr Lansteiner and not young Dr Wiener developed both and only Dr Wiener's ignorant theories connected to Darwin's Theories are responsible for the Rh-Negative vs Anti-Rhesus Blood Factor they should have been named!

In conclusion, I am an example as A-Negative that Rh-Negative Factor People still aren't extinct. Plus... even my son, sister and uncles prove AB-Negatives, though RARE (less than 1%)... are not extinct either. Fact is that though my Portuguese Grandfather off the boat at Ellis Island even with the language difference and obviously being of Basque descent (R1b Haplogroup and subclades of L21, DF13) ended up marrying an Irish girl who was also very rare B-Negative from County Cork, Ireland. Better yet tell me how I passed up so many mates who ended up showing Rh-Positive and picked a B-Negative girl to end up having an ultra-rare.... AB-Negative Son. Who in fact is a rare Universal Plasma and Platelette Donor! ;-P ......Darwin and his Theory of Evolution says that should never have happened with his 'Natural Selection vs Intelligent Design by God! :D


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