Rh-Negative Blood: An Exotic Bloodline or Random Mutation?
Most people who have the Rh blood type are Rh-positive. There are also instances, however, where people are Rh-Negative. Health problems may occur for the unborn child of a mother with Rh-Negative blood when the baby is Rh-Positive. This has led some to suggest that Rh-Negative blood must be of a non-human origin. Theories range from supernatural ones such as being of divine descent or membership in a divinely chosen people-group, to more scientific or pseudoscientific explanations such as interbreeding with extraterrestrials. The majority of scientists who have studied the blood type have concluded that it is most likely just a random mutation. This explanation seems to be the one most consistent with available evidence and the one that is most able to withstand Occam’s Razor.
What is unusual about Rh-Negative blood is that the gene for it is surprisingly common despite being potentially harmful. When a woman who is Rh-Negative is pregnant with a child that is Rh-Positive, the blood from the mother is essentially toxic to the child. To some people, this looks like the mother’s body is rejecting the baby - which has led them to suggest that perhaps the reason for the rejection is incompatibility based on the mother and child being of different species. Others suggest that lineages with the gene for Rh-Negative blood are merely special in some way and were not meant to be mixed with lineages which are predominantly Rh-Positive.
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Blood type testing. (ec-jpr/ CC BY NC ND 2.0 )
Rh-Negative Blood Lineages
One population which contains an unusually high frequency of the gene for the Rh-Negative blood type are the Basques from northeastern Spain. The Basques have the highest incidence of the gene out of any population in the world. The Basques also speak a non-Indo-European language and have genetic markers that pre-date the rise of agriculture. This has led to speculation that Rh-Negative blood is related to Cro-Magnon ancestry going back to the upper Paleolithic period in Europe.
Among the more exotic theories is the idea that the Rh-Negative gene represents a separate branch of humanity that intermarried with the branch that came out of Africa. One blogger has gone as far as to say that those with Rh-Negative blood are descendants of the Hyperborean race, which they believe to be the original human race. Followers of this idea believe that this race was blonde-haired and blue-eyed and included most major spiritual teachers in history, including Jesus.
An artistic representation of Hyperborean women. ( Youtube Screenshot )
Some people who are not satisfied with the idea that those with RH- blood are another form of humanity have suggested that the trait originates from extraterrestrials either interbreeding with humans or creating humans through genetic engineering.
The Role of Genetics in Rh-Negative Blood
This unusual trait can, however, also be explained in terms of relatively mundane human genetics and natural selection. One possibility is that the gene for Rh-Negative blood has some sort of selective advantage that outweighed the negative consequences of having Rh-Negative blood.
A well-known example of this phenomenon would be the case of sickle cell anemia and malaria. A large percentage of the population in west Africa where malaria is common consists of carriers of the gene for sickle-cell anemia, although they don’t have the disease themselves. The reason is that just carrying the gene for sickle cell anemia gives the person carrying it immunity to Malaria. Although sickle-cell anemia is harmful, even deadly, carrying the gene gives a selective advantage and therefore it is much more common than would be expected.
Sickle-cell disease is inherited in the autosomal recessive pattern. ( CC BY SA 3.0 )
Scientists studying the effects of Rh-Negative blood have found that individuals carrying the gene for Rh-Negative blood are more resistant to certain parasites such as toxoplasma, which can threaten unborn children. It has also been found that there are more carriers of the gene in areas where toxoplasma is more common. This suggests that carriers of the gene for Rh-Negative blood might be more common than expected because there is a positive selective advantage, greater resistance to parasites, that outweighs the negative, possibly having a pregnancy where the mother’s blood endangers the unborn child.
Dividing Toxoplasma gondii, an obligate intracellular human parasite. (Ke Hu and John M. Murray/ CC BY 4.0 )