New research published in the journal Nature Genetics has revealed that the origins of tuberculosis (TB) did not emerge around 10,000 years ago in animals and then pass to humans, as currently believed. Rather, the microbe that causes TB appears to have originated with early human ancestors some 70,000 years ago, before their apparent migration from Africa. Throughout history, tuberculosis has been one of the deadliest infectious diseases of humankind. It reached its peak in the 19th and early 20th centuries as an endemic disease of the urban poor and was responsible for one in four deaths in England. Left untreated, TB will kill 50 per cent of the population it infects. Even today, 1 million to 2 million people
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